Uses and limitations of monoclonal antibodies to Giardia lamblia-specific 66-kDa copro-antigen in copro-immunodiagnosis of giardiasis
نویسندگان
چکیده
منابع مشابه
Giardia lamblia and Giardiasis
Introduction Ask the average outdoors person about Giardia lamblia, and they have certainly heard about it. Almost always, however, they are considerably misinformed about both the organism’s significance in wilderness water and the seriousness of the disease, giardiasis, if contracted. The amount of information easily found on the subject is voluminous. Unfortunately, almost all of it is flawe...
متن کاملAntibodies to cysts of Giardia lamblia in primary giardiasis and in the absence of giardiasis.
The significance of serum antibodies binding to cysts of Giardia lamblia was evaluated by indirect immunofluorescence. Titers of 10 or higher were found in 85.6% of adults, who had probably never had giardiasis. Titers in 118 adults (geometric mean, 29.9) were higher than in 35 children (16.4), and titers in women (42.3) were higher than in men (20.0). Titers in 150 patients with primary giardi...
متن کاملComparative Assessment of rEPC1 antigen and Copro-antigen for diagnosis of Echinococcosis in dogs
Abstract BACKGROUND: Diagnosis of Echinococcus granulosus in the definitive host particularly in dog is the significant complication in the endemic area. OBJECTIVES: The aim of this study is serological detection of E. granulosus in the infected dogs. METHODS: Dot-ELISA based on the copro-antigen and recombinant EPC1 antigen (rEPC1) for antibody detection was performed. Blood and fecal samples ...
متن کاملProduction and Characterization of Monoclonal Antibodies Recognizing a Common 57-kDa Antigen of Leishmania Species
Background: The therapy of leishmania infection is difficult and each year 1.5 million new cases of cutaneous leishmaniasis and 500,000 new cases of visceral leishmaniasis are estimated, therefore, there is a need for an effective vaccine. Monoclonal antibody (mAb) is one of the suitable methods for isolation and purification of leishmania antigens. In this report, we produced several mAb aga...
متن کاملDiagnostic Potential of Target Giardia lamblia Specific Antigen for Detection of Human Giardiasis Using Coproantigen Sandwich ELISA
Giardiasis is endemic in all regions of the world. Giardia lamblia (G. lamblia) cysts are spread in Egypt via the fecal-oral route, through ingestion of the cyst with contaminated food or water. The symptoms of giardiasis vary from the asymptomatic passage of cysts to chronic diarrhea, malabsorption and weight loss. Although microscopy has the advantage of low cost and ability to simultaneously...
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ژورنال
عنوان ژورنال: FEMS Immunology and Medical Microbiology
سال: 1993
ISSN: 0928-8244
DOI: 10.1016/0928-8244(93)90030-8